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Adaptive evolution in the toxicity of a spider’s venom enzymes

BACKGROUND: Sphingomyelinase D is the main toxin present in the venom of Loxosceles spiders. Several isoforms present in these venoms can be structurally classified in two groups. Class I Sphingomyelinase D contains a single disulphide bridge and variable loop. Class II Sphingomyelinase D presents a...

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Detalles Bibliográficos
Autores principales: Pedroso, Aurélio, Matioli, Sergio Russo, Murakami, Mario Tyago, Pidde-Queiroz, Giselle, Tambourgi, Denise V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687385/
https://www.ncbi.nlm.nih.gov/pubmed/26690570
http://dx.doi.org/10.1186/s12862-015-0561-4