TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis

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Severe acute pancreatitis (SAP) is an extremely dangerous acute abdominal disorder which causes multiple complications and has a high mortality rate. Previous research has suggested that high-mobility group box 1 (HMGB1) plays an important role in the pathogenesis of SAP; however, the mechanisms und...

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Detalles Bibliográficos
Autores principales: LI, GANG, WU, XUEJUN, YANG, LE, HE, YUXIANG, LIU, YANG, JIN, XING, YUAN, HAI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687439/
https://www.ncbi.nlm.nih.gov/pubmed/26719855
http://dx.doi.org/10.3892/ijmm.2015.2410
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