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A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection

BACKGROUND: Semen is a major vehicle for HIV transmission. Prostatic acid phosphatase (PAP) fragments, such as PAP248-286, in human semen can form amyloid fibrils to enhance HIV infection. Other endogenous or exogenous factors present during sexual intercourse have also been reported to promote the...

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Detalles Bibliográficos
Autores principales: Chen, Jinquan, Ren, Ruxia, Tan, Suiyi, Zhang, Wanyue, Zhang, Xuanxuan, Yu, Fei, Xun, Tianrong, Jiang, Shibo, Liu, Shuwen, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687630/
https://www.ncbi.nlm.nih.gov/pubmed/26656730
http://dx.doi.org/10.1371/journal.pone.0144522