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A Peptide Derived from the HIV-1 gp120 Coreceptor-Binding Region Promotes Formation of PAP248-286 Amyloid Fibrils to Enhance HIV-1 Infection
BACKGROUND: Semen is a major vehicle for HIV transmission. Prostatic acid phosphatase (PAP) fragments, such as PAP248-286, in human semen can form amyloid fibrils to enhance HIV infection. Other endogenous or exogenous factors present during sexual intercourse have also been reported to promote the...
Autores principales: | Chen, Jinquan, Ren, Ruxia, Tan, Suiyi, Zhang, Wanyue, Zhang, Xuanxuan, Yu, Fei, Xun, Tianrong, Jiang, Shibo, Liu, Shuwen, Li, Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687630/ https://www.ncbi.nlm.nih.gov/pubmed/26656730 http://dx.doi.org/10.1371/journal.pone.0144522 |
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