Cargando…

Sitagliptin ameliorates the progression of atherosclerosis via down regulation of the inflammatory and oxidative pathways

BACK GROUND: Atherosclerosis is the major cause of death. The most common risk factors are hyperlipidemia, diabetes, and other factors like chronic infection and inflammation. OBJECTIVE: This study was undertaken to assess the effect of sitagliptin on atherosclerosis via interfering with inflammator...

Descripción completa

Detalles Bibliográficos
Autores principales:	Majeed, Sahar A, Hadi, Najah R, Al Mudhafar, Ahmed M, Al-Janabi, Hussein A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687767/ https://www.ncbi.nlm.nih.gov/pubmed/26770677 http://dx.doi.org/10.1177/2050312113499912

Ejemplares similares

Dipyridamole ameliorates doxorubicin-induced cardiotoxicity
por: Alyasiry, Esraa, et al.
Publicado: (2022)

Potential protective effects of Azelnidipine against cerebral ischemia-reperfusion injury in male rats
por: Fakharaldeen, Zainab, et al.
Publicado: (2022)

Evaluation of the effects of glimepiride (Amaryl) and repaglinide (novoNorm) on atherosclerosis progression in high cholesterol-fed male rabbits
por: Hadi, Najah R., et al.
Publicado: (2012)

The anti-inflammatory and antioxidant effects of Montelukast on lung sepsis in adult mice
por: Alnfakh, Zainab Ali, et al.
Publicado: (2022)

Transthyretin Gene Mutation Associated with Familial Carpal Tunnel Syndrome in Sample of Iraqi Patients
por: Al-Mudhafar, Rihab H., et al.
Publicado: (2021)

Evaluation of anti-atherosclerotic effects of Sitagliptin via modulation of the mTOR pathway in male rabbits
por: Sahib, Hussam Hamza, et al.
Publicado: (2023)

Ultrasonic Assessment of Females with Carpal Tunnel Syndrome Proved by Nerve Conduction Study
por: Ajeena, Ihsan M., et al.
Publicado: (2013)

Xanthohumol ameliorates cardiac injury induced by sepsis in a mice model: role of toll-like receptor 4
por: Hadi, Sarah Mohammed Hussain, et al.
Publicado: (2023)

Berberine Protests the Heart from Ischemic Reperfusion Injury via Interference with Oxidative and Inflammatory Pathways
por: Abdulredha, Abeer, et al.
Publicado: (2021)

Oridonin supplementation attenuates atherosclerosis via NLRP-3 inflammasome pathway suppression
por: Sultan, Ahmed, et al.
Publicado: (2023)

Metformin ameliorates methotrexate-induced hepatotoxicity
por: Hadi, Najah R., et al.
Publicado: (2012)

The effect of evolocumab alone and in combination with atorvastatin on atherosclerosis progression and TLRs expression
por: Saud, Ali, et al.
Publicado: (2023)

The role of cytokines, adhesion molecules, and toll-like receptors in atherosclerosis progression: the effect of Atorvastatin
por: Saud, Ali, et al.
Publicado: (2022)

The effect of JQ1 systemic administration on oxidative stress and apoptotic markers in renal ischemic reperfusion injury in a rat model
por: Younis, Saba Sahib, et al.
Publicado: (2023)

Fimasartan ameliorates renal ischemia reperfusion injury via modulation of oxidative stress, inflammatory and apoptotic cascades in a rat model
por: Abbas, Weaam, et al.
Publicado: (2022)

Oridonin supplementation in rabbits may help to improve the outcome of induced atherosclerosis via autophagy induction
por: Sultan, Ahmed, et al.
Publicado: (2023)

Sitagliptin Successfully Ameliorates Glycemic Control in Werner Syndrome With Diabetes
por: Kitamoto, Takumi, et al.
Publicado: (2012)

Antiapoptotic Effect of Simvastatin Ameliorates Myocardial Ischemia/Reperfusion Injury
por: Hadi, Najah R., et al.
Publicado: (2013)

Vitamin E and telmisartan attenuates doxorubicin induced cardiac injury in rat through down regulation of inflammatory response
por: Hadi, Najah, et al.
Publicado: (2012)

Sitagliptin ameliorates busulfan-induced pulmonary and testicular injury in rats through antioxidant, anti-inflammatory, antifibrotic, and antiapoptotic effects
por: Ali, Eman A., et al.
Publicado: (2023)

Investigation of Anti-Dermatophytic Effects of Non-Steroidal Anti-Inflammatory Drugs on Trichophyton Mentagrophytes and Epidermophyton Floccosum
por: Abdul Hussein, Ali, et al.
Publicado: (2011)

Sitagliptin ameliorates diabetic nephropathy by blocking TGF-β1/Smad signaling pathway
por: Wang, Dongdong, et al.
Publicado: (2018)

NHWD-870 protects the kidney from ischemia/reperfusion injury by upregulating the PI3K/AKT signaling pathway (experimental study)
por: Younis, Saba Sahib, et al.
Publicado: (2023)

Effects of thyroid hormone analogue and a leukotrienes pathway-blocker on renal ischemia/reperfusion injury in mice
por: Hadi, Najah R, et al.
Publicado: (2011)

Leukotriene biosynthesis inhibition ameliorates acute lung injury following hemorrhagic shock in rats
por: Al-Amran, Fadhil G, et al.
Publicado: (2011)

Antidiabetic Drug Sitagliptin with Divalent Transition Metals Manganese and Cobalt: Synthesis, Structure, Characterization Antibacterial and Antioxidative Effects in Liver Tissues
por: El-Megharbel, Samy M., et al.
Publicado: (2022)

The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms
por: Zeng, Yanmei, et al.
Publicado: (2014)

Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats
por: Al-Rasheed, Nouf M, et al.
Publicado: (2016)

Sitagliptin, sitagliptin and metformin, or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats
por: Sharma, Ashish Kumar, et al.
Publicado: (2012)

Sitagliptin ameliorates hypoxia-induced damages in endometrial stromal cells: an implication in endometriosis
por: Li, Ying, et al.
Publicado: (2021)

Dipeptidyl peptidase-4 inhibitor: Sitagliptin down-regulated toll-like receptor 4 signaling pathway to reduce uterine injury in rats
por: Rofaeil, Remon Roshdy, et al.
Publicado: (2022)

Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway
por: Civantos, Esther, et al.
Publicado: (2017)

Effect of Sulforaphane on cardiac injury induced by sepsis in a mouse model: Role of toll-like receptor 4
por: Hadi, Sarah Mohammed Hussain, et al.
Publicado: (2023)

The Effect of Sitagliptin on Carotid Artery Atherosclerosis in Type 2 Diabetes: The PROLOGUE Randomized Controlled Trial
por: Oyama, Jun-ichi, et al.
Publicado: (2016)

Sitagliptin–Moringa oleifera coadministration did not delay the progression nor ameliorated functional and morphological anomalies in alloxan-induced diabetic nephropathy
por: Olurishe, Comfort Omoigemete, et al.
Publicado: (2017)

Hepatoprotective effect of sitagliptin against methotrexate induced liver toxicity
por: Abo-Haded, Hany M., et al.
Publicado: (2017)

Amygdalin ameliorates the progression of atherosclerosis in LDL receptor-deficient mice
por: Lv, Jianzhen, et al.
Publicado: (2017)

Sitagliptin Modulates Oxidative, Nitrative and Halogenative Stress and Inflammatory Response in Rat Model of Hepatic Ischemia-Reperfusion
por: Trocha, Małgorzata, et al.
Publicado: (2021)

Gastrodin ameliorates atherosclerosis by inhibiting foam cells formation and inflammation through down-regulating NF-κB pathway
por: Xue, Xiaofei, et al.
Publicado: (2023)

Synthesis and antifungal activity of novel griseofulvin nanoparticles with zinc oxide against dermatophytic fungi: Trichophyton mentagrophytes and Trichophyton verrucosum: A primary study
por: S. AL-Janabi, Ali Abdul Hussein, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9ilm92395qe9spatks6i0amsk5