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Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South–South Nigeria

BACKGROUND: Stroke causes death and disability worldwide. Hypertension is the most prevalent risk factor. In Nigeria, studies on outcome and risk factors of stroke are from urban-based hospitals. This study aims to look at stroke outcome and the major modifiable risk factors of hospitalized stroke p...

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Autores principales: Okokhere, Peter O, Bankole, Idowu A, Erohubie, Christian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687779/
https://www.ncbi.nlm.nih.gov/pubmed/26770696
http://dx.doi.org/10.1177/2050312113516112
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author Okokhere, Peter O
Bankole, Idowu A
Erohubie, Christian A
author_facet Okokhere, Peter O
Bankole, Idowu A
Erohubie, Christian A
author_sort Okokhere, Peter O
collection PubMed
description BACKGROUND: Stroke causes death and disability worldwide. Hypertension is the most prevalent risk factor. In Nigeria, studies on outcome and risk factors of stroke are from urban-based hospitals. This study aims to look at stroke outcome and the major modifiable risk factors of hospitalized stroke patients in semi-urban Nigeria. METHODS: The medical records of stroke patients admitted between March 2008 and February 2010 were reviewed retrospectively. The relevant demographic, clinical and laboratory data of each patient were retrieved. RESULTS: A total of 99 cases of stroke made up of 51 males and 48 females were reviewed. Mean age of the subjects was 66.22 ± 12.67 years. Mean systolic blood pressure and diastolic blood pressure at presentation were 171.41 ± 39.10 mmHg and 100.44 ± 21 mmHg, respectively. About 61.6% were known hypertensives, while 31.3%, not previously known to be hypertensive, had SBP ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Overall, 85.9% of the subjects had SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg. In all, 46.5% had SBP ≥ 180 mmHg, and 63% of this number had SBP ≥ 200 mmHg; 42.4% had DBP ≥ 110 mmHg. Other major risk factors were hypercholesterolaemia (34.4%), diabetes mellitus (16.6%), previous cerebrovascular accident (15.2%) and smoking (9.4%). In all, 31.3% had two or more modifiable stroke risk factors. 36.4% of the subjects were comatose. Overall case fatality rate was 45.8%, 75% of the subjects with coma died, compared to 27.6% without coma (p < 0.01). CONCLUSION: Mortality in our stroke patients is high. Hypertension is the commonest modifiable risk factor, and the presence of coma at presentation is associated with poor prognosis.
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spelling pubmed-46877792016-01-14 Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South–South Nigeria Okokhere, Peter O Bankole, Idowu A Erohubie, Christian A SAGE Open Med Original Article BACKGROUND: Stroke causes death and disability worldwide. Hypertension is the most prevalent risk factor. In Nigeria, studies on outcome and risk factors of stroke are from urban-based hospitals. This study aims to look at stroke outcome and the major modifiable risk factors of hospitalized stroke patients in semi-urban Nigeria. METHODS: The medical records of stroke patients admitted between March 2008 and February 2010 were reviewed retrospectively. The relevant demographic, clinical and laboratory data of each patient were retrieved. RESULTS: A total of 99 cases of stroke made up of 51 males and 48 females were reviewed. Mean age of the subjects was 66.22 ± 12.67 years. Mean systolic blood pressure and diastolic blood pressure at presentation were 171.41 ± 39.10 mmHg and 100.44 ± 21 mmHg, respectively. About 61.6% were known hypertensives, while 31.3%, not previously known to be hypertensive, had SBP ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg. Overall, 85.9% of the subjects had SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg. In all, 46.5% had SBP ≥ 180 mmHg, and 63% of this number had SBP ≥ 200 mmHg; 42.4% had DBP ≥ 110 mmHg. Other major risk factors were hypercholesterolaemia (34.4%), diabetes mellitus (16.6%), previous cerebrovascular accident (15.2%) and smoking (9.4%). In all, 31.3% had two or more modifiable stroke risk factors. 36.4% of the subjects were comatose. Overall case fatality rate was 45.8%, 75% of the subjects with coma died, compared to 27.6% without coma (p < 0.01). CONCLUSION: Mortality in our stroke patients is high. Hypertension is the commonest modifiable risk factor, and the presence of coma at presentation is associated with poor prognosis. SAGE Publications 2013-12-11 /pmc/articles/PMC4687779/ /pubmed/26770696 http://dx.doi.org/10.1177/2050312113516112 Text en © The Author(s) 2013 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(http://www.uk.sagepub.com/aboutus/openaccess.htm).
spellingShingle Original Article
Okokhere, Peter O
Bankole, Idowu A
Erohubie, Christian A
Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South–South Nigeria
title Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South–South Nigeria
title_full Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South–South Nigeria
title_fullStr Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South–South Nigeria
title_full_unstemmed Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South–South Nigeria
title_short Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South–South Nigeria
title_sort characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban south–south nigeria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687779/
https://www.ncbi.nlm.nih.gov/pubmed/26770696
http://dx.doi.org/10.1177/2050312113516112
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