Mutational Landscapes of Sequential Prostate Metastases and Matched Patient Derived Xenografts during Enzalutamide Therapy

Developing patient derived models from individual tumors that capture the biological heterogeneity and mutation landscape in advanced prostate cancer is challenging, but essential for understanding tumor progression and delivery of personalized therapy in metastatic castrate resistant prostate cance...

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Detalles Bibliográficos
Autores principales: Kohli, Manish, Wang, Liguo, Xie, Fang, Sicotte, Hugues, Yin, Ping, Dehm, Scott M., Hart, Steven N., Vedell, Peter T., Barman, Poulami, Qin, Rui, Mahoney, Douglas W., Carlson, Rachel E., Eckel-Passow, Jeanette E., Atwell, Thomas D., Eiken, Patrick W., McMenomy, Brendan P., Wieben, Eric D., Jha, Gautam, Jimenez, Rafael E., Weinshilboum, Richard, Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687867/
https://www.ncbi.nlm.nih.gov/pubmed/26695660
http://dx.doi.org/10.1371/journal.pone.0145176

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