Cargando…

The actin-binding protein EPS8 binds VE-cadherin and modulates YAP localization and signaling

Vascular endothelial (VE)–cadherin transfers intracellular signals contributing to vascular hemostasis. Signaling through VE-cadherin requires association and activity of different intracellular partners. Yes-associated protein (YAP)/TAZ transcriptional cofactors are important regulators of cell gro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giampietro, Costanza, Disanza, Andrea, Bravi, Luca, Barrios-Rodiles, Miriam, Corada, Monica, Frittoli, Emanuela, Savorani, Cecilia, Lampugnani, Maria Grazia, Boggetti, Barbara, Niessen, Carien, Wrana, Jeff L., Scita, Giorgio, Dejana, Elisabetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687874/ https://www.ncbi.nlm.nih.gov/pubmed/26668327 http://dx.doi.org/10.1083/jcb.201501089

Ejemplares similares

Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo
por: Orsenigo, Fabrizio, et al.
Publicado: (2012)

Differential Localization of VE- and N-Cadherins in Human Endothelial Cells: VE-Cadherin Competes with N-Cadherin for Junctional Localization
por: Navarro, Pilar, et al.
Publicado: (1998)

VE-Cadherin–Mediated Epigenetic Regulation of Endothelial Gene Expression
por: Morini, Marco F., et al.
Publicado: (2018)

Cadherin-mediated cell sorting not determined by binding or adhesion specificity
por: Niessen, Carien M., et al.
Publicado: (2002)

Partial loss of VE-cadherin improves long-term outcome and cerebral blood flow after transient brain ischemia in mice
por: Gertz, Karen, et al.
Publicado: (2016)

E-cadherin binds to desmoglein to facilitate desmosome assembly
por: Shafraz, Omer, et al.
Publicado: (2018)

A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition
por: Savorani, Cecilia, et al.
Publicado: (2021)

Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, β-catenin, and the phosphatase DEP-1/CD148
por: Lampugnani, Maria Grazia, et al.
Publicado: (2003)

Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex
por: Coon, Brian G., et al.
Publicado: (2015)

The role of microvascular endothelial WNT signaling the formation of the blood brain barrier
por: Lampugnani, Maria Grazia, et al.
Publicado: (2015)

Stable Vascular Connections and Remodeling Require Full Expression of VE-Cadherin in Zebrafish Embryos
por: Montero-Balaguer, Mercedes, et al.
Publicado: (2009)

Eps8 Regulates Axonal Filopodia in Hippocampal Neurons in Response to Brain-Derived Neurotrophic Factor (BDNF)
por: Menna, Elisabetta, et al.
Publicado: (2009)

Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin
por: Smith, Ross O, et al.
Publicado: (2020)

Correction: Eps8 Regulates Axonal Filopodia in Hippocampal Neurons in Response to Brain-Derived Neurotrophic Factor (BDNF)
por: Menna, Elisabetta, et al.
Publicado: (2015)

How VE-cadherin goes with the flow
por: Short, Ben
Publicado: (2015)

N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis
por: Luo, Yang, et al.
Publicado: (2005)

Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments
por: Lampugnani, Maria Grazia, et al.
Publicado: (2006)

The RNA-binding protein quaking maintains endothelial barrier function and affects VE-cadherin and β-catenin protein expression
por: de Bruin, Ruben G., et al.
Publicado: (2016)

KLF4 is a key determinant in the development and progression of cerebral cavernous malformations
por: Cuttano, Roberto, et al.
Publicado: (2015)

HIF-2α promotes the formation of vasculogenic mimicry in pancreatic cancer by regulating the binding of Twist1 to the VE-cadherin promoter
por: Yang, Jian, et al.
Publicado: (2017)

Endothelial Phosphatase VE-PTP Participates in Vasculogenic Mimicry by Preventing Autophagic Degradation of VE-Cadherin
por: Delgado-Bellido, Daniel, et al.
Publicado: (2020)

Endothelial permeability and VE-cadherin: A wacky comradeship
por: Gavard, Julie
Publicado: (2014)

VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance
por: Yang, Ying, et al.
Publicado: (2019)

The cadherin-binding specificities of B-cadherin and LCAM
Publicado: (1995)

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1
por: Innocenti, Metello, et al.
Publicado: (2003)

The Eps8/IRSp53/VASP Network Differentially Controls Actin Capping and Bundling in Filopodia Formation
por: Vaggi, Federico, et al.
Publicado: (2011)

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin
por: Frye, Maike, et al.
Publicado: (2015)

VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism
por: Juettner, Vanessa V., et al.
Publicado: (2019)

Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling
por: Knop, Juna-Lisa, et al.
Publicado: (2023)

Ve-ptp Modulates Vascular Integrity by Promoting Adherens Junction Maturation
por: Carra, Silvia, et al.
Publicado: (2012)

Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions
por: Tiruppathi, Chinnaswamy, et al.
Publicado: (2023)

Antitumor immunity induced by VE-cadherin modified DC vaccine
por: Zhou, Jing, et al.
Publicado: (2017)

Mechanisms Ensuring Endothelial Junction Integrity Beyond VE-Cadherin
por: Duong, Cao Nguyen, et al.
Publicado: (2020)

Extracellular matrix regulates force transduction at VE-cadherin junctions
por: Kong, Xinyu, et al.
Publicado: (2022)

Leptospira interrogans Binds to Cadherins
por: Evangelista, Karen, et al.
Publicado: (2014)

The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120(ctn)
por: Yap, Alpha S., et al.
Publicado: (1998)

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF
por: Nottebaum, Astrid F., et al.
Publicado: (2008)

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo
por: Broermann, Andre, et al.
Publicado: (2011)

Intermedin promotes vessel fusion by inducing VE‐cadherin accumulation at potential fusion sites and to achieve a dynamic balance between VE‐cadherin‐complex dissociation/reconstitution
por: Kong, Lingmiao, et al.
Publicado: (2020)

Alpha Yap: Cadherins hold it all together
por: Sedwick, Caitlin
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_lvm13jorjtjcrr34p0b5783beh