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Thirty years of search and capture: The complex simplicity of mitotic spindle assembly
Cell division is enacted by a microtubule-based, self-assembling macromolecular machine known as the mitotic spindle. In 1986, Kirschner and Mitchison proposed that by undergoing dynamic cycles of growth and disassembly, microtubules search for chromosomes. Capture of microtubules by the kinetochore...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687881/ https://www.ncbi.nlm.nih.gov/pubmed/26668328 http://dx.doi.org/10.1083/jcb.201510015 |