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TAK1-dependent autophagy: A suppressor of fatty liver disease and hepatic oncogenesis
In addition to regulating the activation of nuclear factor (NF)-κB and c-Jun N-terminal kinase (JNK), TGF-β activated kinase 1 (TAK1) also upregulates the activation of AMP-activated protein kinase (AMPK) and autophagy. In the liver, TAK1-mediated autophagy plays a role in preventing excessive lipid...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687902/ https://www.ncbi.nlm.nih.gov/pubmed/26709386 http://dx.doi.org/10.4161/23723548.2014.968507 |