PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage

A2E and related toxic molecules are part of lipofuscin found in the retinal pigment epithelial (RPE) cells in eyes affected by Stargardt’s disease, age-related macular degeneration (AMD), and other retinal degenerations. A novel therapeutic approach for treating such degenerations involves slowing d...

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Detalles Bibliográficos
Autores principales: Stiles, Megan, Moiseyev, Gennadiy P., Budda, Madeline L., Linens, Annette, Brush, Richard S., Qi, Hui, White, Gary L., Wolf, Roman F., Ma, Jian-xing, Floyd, Robert, Anderson, Robert E., Mandal, Nawajes A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687940/
https://www.ncbi.nlm.nih.gov/pubmed/26694648
http://dx.doi.org/10.1371/journal.pone.0145305

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