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Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis

Introduction The relevance of allergic rhinitis is unquestionable. This condition affects people's quality of life and its incidence has increased over the last years. Objective Thus, this study aims to analyze the effectiveness of subcutaneous injectable immunotherapy in cases of nasal itching...

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Autores principales: Lourenço, Edmir Américo, Caldeira, Eduardo José, Carvalho, César Alexandre Fabrega, Cunha, Marcelo Rodriques, Carvalho, Marcus Vinícius Henriques, Passos, Saulo Duarte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Publicações Ltda 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688001/
https://www.ncbi.nlm.nih.gov/pubmed/26722338
http://dx.doi.org/10.1055/s-0035-1564437
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author Lourenço, Edmir Américo
Caldeira, Eduardo José
Carvalho, César Alexandre Fabrega
Cunha, Marcelo Rodriques
Carvalho, Marcus Vinícius Henriques
Passos, Saulo Duarte
author_facet Lourenço, Edmir Américo
Caldeira, Eduardo José
Carvalho, César Alexandre Fabrega
Cunha, Marcelo Rodriques
Carvalho, Marcus Vinícius Henriques
Passos, Saulo Duarte
author_sort Lourenço, Edmir Américo
collection PubMed
description Introduction The relevance of allergic rhinitis is unquestionable. This condition affects people's quality of life and its incidence has increased over the last years. Objective Thus, this study aims to analyze the effectiveness of subcutaneous injectable immunotherapy in cases of nasal itching, sneeze, rhinorrhea and nasal congestion in allergic rhinitis patients. Methods In the present study, the same researcher analyzed the records of 281 patients. Furthermore, the researchers identified allergens through puncture cutaneous tests using standardized extracts containing acari, fungi, pet hair, flower pollen, and feathers. Then, the patients underwent treatment with subcutaneous specific immunotherapy, using four vaccine vials for desensitization, associated with environmental hygiene. The authors analyzed conditions of nasal itching, sneeze, rhinorrhea, and nasal congestion throughout the treatment, and assigned them with a score ranging from zero (0), meaning absence of these symptoms to three (3), for severe cases. The symptoms were statistically compared in the beginning, during, and after treatment. Results In this study, authors analyzed the cases distribution according to age and the evolution of symptomatology according to the scores, comparing all phases of treatment. The average score for the entire population studied was 2.08 before treatment and 0.44 at the end. These results represent an overall improvement of ∼79% in symptomatology of allergic rhinitis in the studied population. Conclusion The subcutaneous immunotherapy as treatment of allergic rhinitis led to a reduction in all symptoms studied, improving the quality of life of patients, proving itself as an important therapeutic tool for these pathological conditions.
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spelling pubmed-46880012016-01-01 Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis Lourenço, Edmir Américo Caldeira, Eduardo José Carvalho, César Alexandre Fabrega Cunha, Marcelo Rodriques Carvalho, Marcus Vinícius Henriques Passos, Saulo Duarte Int Arch Otorhinolaryngol Article Introduction The relevance of allergic rhinitis is unquestionable. This condition affects people's quality of life and its incidence has increased over the last years. Objective Thus, this study aims to analyze the effectiveness of subcutaneous injectable immunotherapy in cases of nasal itching, sneeze, rhinorrhea and nasal congestion in allergic rhinitis patients. Methods In the present study, the same researcher analyzed the records of 281 patients. Furthermore, the researchers identified allergens through puncture cutaneous tests using standardized extracts containing acari, fungi, pet hair, flower pollen, and feathers. Then, the patients underwent treatment with subcutaneous specific immunotherapy, using four vaccine vials for desensitization, associated with environmental hygiene. The authors analyzed conditions of nasal itching, sneeze, rhinorrhea, and nasal congestion throughout the treatment, and assigned them with a score ranging from zero (0), meaning absence of these symptoms to three (3), for severe cases. The symptoms were statistically compared in the beginning, during, and after treatment. Results In this study, authors analyzed the cases distribution according to age and the evolution of symptomatology according to the scores, comparing all phases of treatment. The average score for the entire population studied was 2.08 before treatment and 0.44 at the end. These results represent an overall improvement of ∼79% in symptomatology of allergic rhinitis in the studied population. Conclusion The subcutaneous immunotherapy as treatment of allergic rhinitis led to a reduction in all symptoms studied, improving the quality of life of patients, proving itself as an important therapeutic tool for these pathological conditions. Thieme Publicações Ltda 2015-10-07 2016-01 /pmc/articles/PMC4688001/ /pubmed/26722338 http://dx.doi.org/10.1055/s-0035-1564437 Text en © Thieme Medical Publishers
spellingShingle Article
Lourenço, Edmir Américo
Caldeira, Eduardo José
Carvalho, César Alexandre Fabrega
Cunha, Marcelo Rodriques
Carvalho, Marcus Vinícius Henriques
Passos, Saulo Duarte
Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis
title Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis
title_full Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis
title_fullStr Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis
title_full_unstemmed Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis
title_short Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis
title_sort subcutaneous immunotherapy improves the symptomatology of allergic rhinitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688001/
https://www.ncbi.nlm.nih.gov/pubmed/26722338
http://dx.doi.org/10.1055/s-0035-1564437
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