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The role of spleen in the treatment of experimental lipopolysaccharide-induced sepsis with dexmedetomidine

Dexmedetomidine (Dex), a highly selective α2-adrenergic receptor agonist, has been shown to attenuate systemic inflammatory response induced by lipopolysaccharide (LPS). The protective effects of Dex may reportedly be due to the activation of the α7 nicotinic acetylcholine receptor (α7nAChR)-depende...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoguo, Wang, Yaoqi, Ning, Qiaoqing, Gong, Chunzhi, Zhang, Yong, Zhang, Li, Bu, Xiangmei, Jing, Guangjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688290/
https://www.ncbi.nlm.nih.gov/pubmed/26702389
http://dx.doi.org/10.1186/s40064-015-1598-y