Cargando…

The role of spleen in the treatment of experimental lipopolysaccharide-induced sepsis with dexmedetomidine

Dexmedetomidine (Dex), a highly selective α2-adrenergic receptor agonist, has been shown to attenuate systemic inflammatory response induced by lipopolysaccharide (LPS). The protective effects of Dex may reportedly be due to the activation of the α7 nicotinic acetylcholine receptor (α7nAChR)-depende...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Zhaoguo, Wang, Yaoqi, Ning, Qiaoqing, Gong, Chunzhi, Zhang, Yong, Zhang, Li, Bu, Xiangmei, Jing, Guangjian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688290/ https://www.ncbi.nlm.nih.gov/pubmed/26702389 http://dx.doi.org/10.1186/s40064-015-1598-y

Ejemplares similares

Pathway-related modules involved in the application of sevoflurane or propofol in off-pump coronary artery bypass graft surgery
por: Bu, Xiangmei, et al.
Publicado: (2017)

Dexmedetomidine Attenuates Lipopolysaccharide-Induced Sympathetic Activation and Sepsis via Suppressing Superoxide Signaling in Paraventricular Nucleus
por: Bo, Jin-Hua, et al.
Publicado: (2022)

Hyperin protects against LPS-induced acute kidney injury by inhibiting TLR4 and NLRP3 signaling pathways
por: Chunzhi, Gong, et al.
Publicado: (2016)

Dexmedetomidine Alleviates Microglia-Induced Spinal Inflammation and Hyperalgesia in Neonatal Rats by Systemic Lipopolysaccharide Exposure
por: Wen, Wen, et al.
Publicado: (2021)

Effect of dexmedetomidine on intrapulmonary shunt in patients with sevoflurane maintained during one-lung ventilation: A case–control study
por: Wang, Yewen, et al.
Publicado: (2022)

The Antinociceptive Effect of Dexmedetomidine Modulates Spleen Cell Immunity in Mice
por: Jang, Yeon, et al.
Publicado: (2014)

STUDIES ON THE RÔLE OF THE SPLEEN IN EXPERIMENTAL POLIOMYELITIS
por: Lennette, Edwin H.
Publicado: (1937)

Pharmacological implications of the spleen in sepsis
por: Cai, Bolin, et al.
Publicado: (2007)

Dexmedetomidine reduces lipopolysaccharide induced neuroinflammation, sickness behavior, and anhedonia
por: Yeh, Ching-Hua, et al.
Publicado: (2018)

Dexmedetomidine alleviates lipopolysaccharide-induced lung injury in Wistar rats
por: Yan, Xuetao, et al.
Publicado: (2017)

Role of the Sympathetic Nervous System and Spleen in Experimental Stroke-Induced Immunodepression
por: Yan, Fu-Ling, et al.
Publicado: (2014)

Dexmedetomidine Attenuates Lipopolysaccharide Induced MCP-1 Expression in Primary Astrocyte
por: Liu, Huan, et al.
Publicado: (2017)

Dexmedetomidine improves the outcomes for pediatric severe sepsis with mechanical ventilation
por: Zhao, Chun, et al.
Publicado: (2023)

Dexmedetomidine attenuates inflammation and organ injury partially by upregulating Nur77 in sepsis
por: Zhang, Qian, et al.
Publicado: (2023)

Paclitaxel inhibits the hyper-activation of spleen cells by lipopolysaccharide and induces cell death
por: Kim, Hyun-Ji, et al.
Publicado: (2016)

Dexmedetomidine Prevents Lipopolysaccharide-Induced MicroRNA Expression in the Adult Rat Brain
por: Paeschke, Nadine, et al.
Publicado: (2017)

Effect of sedation with dexmedetomidine or propofol on gastrointestinal motility in lipopolysaccharide-induced endotoxemic mice
por: Chang, Haiqing, et al.
Publicado: (2020)

Dexmedetomidine alleviated sepsis-induced myocardial ferroptosis and septic heart injury
por: Wang, Chunyan, et al.
Publicado: (2020)

0729. Interstitial changes in spleen during sepsis
por: Svendsen, ØS, et al.
Publicado: (2014)

Stellate Ganglion Block Combined with Dexmedetomidine Protects Obese Rats from Lipopolysaccharide-Induced Acute Lung Injury
por: Zhang, Weiwei, et al.
Publicado: (2022)

Norcantharidin down-regulates iron contents in the liver and spleen of lipopolysaccharide-treated mice
por: Zheng, Jie, et al.
Publicado: (2022)

Dexmedetomidine attenuates lipopolysaccharide-induced acute liver injury in rats by inhibiting caveolin-1 downstream signaling pathway
por: Tong, Fei, et al.
Publicado: (2021)

Dexmedetomidine Alleviates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting p75NTR-Mediated Oxidative Stress and Apoptosis
por: Wang, Zhe, et al.
Publicado: (2020)

Toddalolactone Protects Lipopolysaccharide-Induced Sepsis and Attenuates Lipopolysaccharide-Induced Inflammatory Response by Modulating HMGB1-NF-κB Translocation
por: Ni, Jingyu, et al.
Publicado: (2020)

The Expression and Clinical Significance of Spleen Tyrosine Kinase in Patients with Coronary Heart Disease
por: Liang, Ke, et al.
Publicado: (2019)

Hemp Seed Fermented by Aspergillus oryzae Attenuates Lipopolysaccharide-Stimulated Inflammatory Responses in N9 Microglial Cells
por: Wang, Zeyuan, et al.
Publicado: (2022)

Blood-Brain Barrier Disruption by Lipopolysaccharide and Sepsis-Associated Encephalopathy
por: Peng, Xiaoyao, et al.
Publicado: (2021)

Dexmedetomidine May Produce Extra Protective Effects on Sepsis-induced Diaphragm Injury
por: Wu, Jin, et al.
Publicado: (2015)

The hydroxy-analogue of selenomethionine alleviated lipopolysaccharide-induced inflammatory responses is associated with recover expression of several selenoprotein encoding genes in the spleens of Kunming mice
por: Tang, Jia-Yong, et al.
Publicado: (2019)

Necroptosis Underlies Hepatic Damage in a Piglet Model of Lipopolysaccharide-Induced Sepsis
por: Xu, Qiao, et al.
Publicado: (2021)

Decrease of Plasma Platelet-Activating Factor Acetylhydrolase Activity in Lipopolysaccharide Induced Mongolian Gerbil Sepsis Model
por: Yang, Junwei, et al.
Publicado: (2010)

Dexmedetomidine ameliorates lipopolysaccharide-induced acute lung injury by inhibiting the PI3K/Akt/FoxO1 signaling pathway
por: Cui, Haibin, et al.
Publicado: (2021)

Comparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver
por: Smolinski, Alexa T, et al.
Publicado: (2005)

Frequency of expressed immunoglobulin light chain genes in lipopolysaccharide-stimulated BALB/c spleen cells
Publicado: (1984)

Loss of Sympathetic Nerves in Spleens from Patients with End Stage Sepsis
por: Hoover, Donald B., et al.
Publicado: (2017)

Efficacy of dexmedetomidine for treatment of patients with sepsis: A meta-analysis of randomized controlled trials
por: Zhang, Wen-Qing, et al.
Publicado: (2019)

Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats
por: Fu, Chunlai, et al.
Publicado: (2017)

Dose-related effects of dexmedetomidine on sepsis-initiated lung injury in rats
por: Karabulut, Gülsüm, et al.
Publicado: (2021)

Effect of Electroacupuncture at Zusanli (ST36) on Sepsis Induced by Cecal Ligation Puncture and Its Relevance to Spleen
por: Xie, Dong-ping, et al.
Publicado: (2020)

Lipopolysaccharide adsorption in combined therapy of patients with severe sepsis
por: Yaroustovsky, M, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_dm56j7skeu8q4rfoi4grr1srn7