Expression of the Multimeric and Highly Immunogenic Brucella spp. Lumazine Synthase Fused to Bovine Rotavirus VP8d as a Scaffold for Antigen Production in Tobacco Chloroplasts

Lumazine synthase from Brucella spp. (BLS) is a highly immunogenic decameric protein which can accommodate foreign polypeptides or protein domains fused to its N-termini, markedly increasing their immunogenicity. The inner core domain (VP8d) of VP8 spike protein from bovine rotavirus is responsible...

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Detalles Bibliográficos
Autores principales: Alfano, E. Federico, Lentz, Ezequiel M., Bellido, Demian, Dus Santos, María J., Goldbaum, Fernando A., Wigdorovitz, Andrés, Bravo-Almonacid, Fernando F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688359/
https://www.ncbi.nlm.nih.gov/pubmed/26779198
http://dx.doi.org/10.3389/fpls.2015.01170

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