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Simulation of Cl(−) Secretion in Epithelial Tissues: New Methodology Estimating Activity of Electro-Neutral Cl(−) Transporter
Transcellular Cl(−) secretion is, in general, mediated by two steps; (1) the entry step of Cl(−) into the cytosolic space from the basolateral space across the basolateral membrane by Cl(−) transporters, such as Na(+)-K(+)-2Cl(−) cotransporter (NKCC1, an isoform of NKCC), and (2) the releasing step...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688368/ https://www.ncbi.nlm.nih.gov/pubmed/26779025 http://dx.doi.org/10.3389/fphys.2015.00370 |