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A Network-Based Model of Oncogenic Collaboration for Prediction of Drug Sensitivity

Tumorigenesis is a multi-step process, involving the acquisition of multiple oncogenic mutations that transform cells, resulting in systemic dysregulation that enables proliferation, invasion, and other cancer hallmarks. The goal of precision medicine is to identify therapeutically-actionable mutati...

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Detalles Bibliográficos
Autores principales: Laderas, Ted G., Heiser, Laura M., Sönmez, Kemal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688377/
https://www.ncbi.nlm.nih.gov/pubmed/26779250
http://dx.doi.org/10.3389/fgene.2015.00341