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A Network-Based Model of Oncogenic Collaboration for Prediction of Drug Sensitivity
Tumorigenesis is a multi-step process, involving the acquisition of multiple oncogenic mutations that transform cells, resulting in systemic dysregulation that enables proliferation, invasion, and other cancer hallmarks. The goal of precision medicine is to identify therapeutically-actionable mutati...
Autores principales: | Laderas, Ted G., Heiser, Laura M., Sönmez, Kemal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688377/ https://www.ncbi.nlm.nih.gov/pubmed/26779250 http://dx.doi.org/10.3389/fgene.2015.00341 |
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