Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells

The antitumor drug etoposide (ETO) is widely used in treating several cancers, including adrenocortical tumor (ACT). However, when used at sublethal doses, tumor cells still survive and are more susceptible to the recurring tumor due to centrosome amplification. Here, we checked the effect of sublet...

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Detalles Bibliográficos
Autores principales: Chen, T-Y, Syu, J-S, Lin, T-C, Cheng, H-l, Lu, F-l, Wang, C-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688395/
https://www.ncbi.nlm.nih.gov/pubmed/26690546
http://dx.doi.org/10.1038/oncsis.2015.37

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