Glycosylation characterization of therapeutic mAbs by top- and middle-down mass spectrometry

A reference monoclonal antibody IgG1 and a fusion IgG protein were analyzed by top- and middle-down mass spectrometry with multiple fragmentation techniques including electron transfer dissociation (ETD) and matrix-assisted laser desorption ionization in-source decay (MALDI-ISD) to investigate heter...

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Detalles Bibliográficos
Autores principales: Tran, Bao Quoc, Barton, Christopher, Feng, Jinhua, Sandjong, Aimee, Yoon, Sung Hwan, Awasthi, Shivangi, Liang, Tao, Khan, Mohd M., Kilgour, David P.A., Goodlett, David R., Goo, Young Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688415/
https://www.ncbi.nlm.nih.gov/pubmed/26793758
http://dx.doi.org/10.1016/j.dib.2015.11.031

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