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Identification of Small Molecule Inhibitors of Human As(III) S-Adenosylmethionine Methyltransferase (AS3MT)

[Image: see text] Arsenic is the most ubiquitous environmental toxin and carcinogen. Long-term exposure to arsenic is associated with human diseases including cancer, cardiovascular disease, and diabetes. Human As(III) S-adenosylmethionine (SAM) methyltransferases (hAS3MT) methylates As(III) to triv...

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Detalles Bibliográficos
Autores principales:	Dong, Hui, Madegowda, Mahendra, Nefzi, Adel, Houghten, Richard A., Giulianotti, Marc A., Rosen, Barry P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688878/ https://www.ncbi.nlm.nih.gov/pubmed/26577531 http://dx.doi.org/10.1021/acs.chemrestox.5b00432

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