Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature

• Bevacizumab was an effective agent in one case of advanced uterine PNET. • VEGF was expressed by the tumor, supporting a mechanism for effectiveness. • Cisplatin/etoposide/bevacizumab should be further studied in clinical trials. • Patient remains disease-free forty-eight months following interven...

Descripción completa

Detalles Bibliográficos
Autores principales: Novo, Jorge, Bitterman, Pincas, Guirguis, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688884/
https://www.ncbi.nlm.nih.gov/pubmed/26793768
http://dx.doi.org/10.1016/j.gore.2015.09.002
Descripción
Sumario:• Bevacizumab was an effective agent in one case of advanced uterine PNET. • VEGF was expressed by the tumor, supporting a mechanism for effectiveness. • Cisplatin/etoposide/bevacizumab should be further studied in clinical trials. • Patient remains disease-free forty-eight months following intervention.

Ejemplares similares