Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature

• Bevacizumab was an effective agent in one case of advanced uterine PNET. • VEGF was expressed by the tumor, supporting a mechanism for effectiveness. • Cisplatin/etoposide/bevacizumab should be further studied in clinical trials. • Patient remains disease-free forty-eight months following interven...

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Detalles Bibliográficos
Autores principales: Novo, Jorge, Bitterman, Pincas, Guirguis, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688884/
https://www.ncbi.nlm.nih.gov/pubmed/26793768
http://dx.doi.org/10.1016/j.gore.2015.09.002
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author Novo, Jorge
Bitterman, Pincas
Guirguis, Alfred
author_facet Novo, Jorge
Bitterman, Pincas
Guirguis, Alfred
author_sort Novo, Jorge
collection PubMed
description • Bevacizumab was an effective agent in one case of advanced uterine PNET. • VEGF was expressed by the tumor, supporting a mechanism for effectiveness. • Cisplatin/etoposide/bevacizumab should be further studied in clinical trials. • Patient remains disease-free forty-eight months following intervention.
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spelling pubmed-46888842016-01-20 Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature Novo, Jorge Bitterman, Pincas Guirguis, Alfred Gynecol Oncol Rep Case Report • Bevacizumab was an effective agent in one case of advanced uterine PNET. • VEGF was expressed by the tumor, supporting a mechanism for effectiveness. • Cisplatin/etoposide/bevacizumab should be further studied in clinical trials. • Patient remains disease-free forty-eight months following intervention. Elsevier 2015-09-16 /pmc/articles/PMC4688884/ /pubmed/26793768 http://dx.doi.org/10.1016/j.gore.2015.09.002 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Novo, Jorge
Bitterman, Pincas
Guirguis, Alfred
Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature
title Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature
title_full Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature
title_fullStr Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature
title_full_unstemmed Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature
title_short Central-type primitive neuroectodermal tumor of the uterus: Case report of remission of stage IV disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature
title_sort central-type primitive neuroectodermal tumor of the uterus: case report of remission of stage iv disease using adjuvant cisplatin/etoposide/bevacizumab chemotherapy and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688884/
https://www.ncbi.nlm.nih.gov/pubmed/26793768
http://dx.doi.org/10.1016/j.gore.2015.09.002
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