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Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism
BACKGROUND: Insulin sensitivity in skeletal muscle is associated with metabolic flexibility, including a high capacity to increase fatty acid (FA) oxidation in response to increased lipid supply. Lipid overload, however, can result in incomplete FA oxidation and accumulation of potentially harmful i...
Autores principales: | Ashmore, Tom, Roberts, Lee D., Morash, Andrea J., Kotwica, Aleksandra O., Finnerty, John, West, James A., Murfitt, Steven A., Fernandez, Bernadette O., Branco, Cristina, Cowburn, Andrew S., Clarke, Kieran, Johnson, Randall S., Feelisch, Martin, Griffin, Julian L., Murray, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688964/ https://www.ncbi.nlm.nih.gov/pubmed/26694920 http://dx.doi.org/10.1186/s12915-015-0221-6 |
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