A rare case of isoniazid-induced erythroderma

Tuberculosis is a common infectious disease in developing countries. Isoniazid is established the first-line antitubercular drug and an essential component of all antitubercular regimens. Erythroderma caused by isoniazid is an uncommon but serious adverse drug reaction. We report here a case of a 63...

Descripción completa

Detalles Bibliográficos
Autores principales: Garg, Yashika, Gore, Rajeshwari, Jain, Sourabh, Kumar, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689027/
https://www.ncbi.nlm.nih.gov/pubmed/26729965
http://dx.doi.org/10.4103/0253-7613.169575
_version_ 1782406781809459200
author Garg, Yashika
Gore, Rajeshwari
Jain, Sourabh
Kumar, Arun
author_facet Garg, Yashika
Gore, Rajeshwari
Jain, Sourabh
Kumar, Arun
author_sort Garg, Yashika
collection PubMed
description Tuberculosis is a common infectious disease in developing countries. Isoniazid is established the first-line antitubercular drug and an essential component of all antitubercular regimens. Erythroderma caused by isoniazid is an uncommon but serious adverse drug reaction. We report here a case of a 63-year-old female patient who presented with generalized redness and scaling with itching after 8 weeks of antitubercular treatment (ATT). ATT was stopped immediately, and antihistaminics were started. The patient improved over a period of 2 weeks. On sequential rechallenge, she developed similar lesions all over the body with isoniazid, hence confirming the diagnosis of isoniazid-induced erythroderma.
format Online
Article
Text
id pubmed-4689027
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-46890272016-01-04 A rare case of isoniazid-induced erythroderma Garg, Yashika Gore, Rajeshwari Jain, Sourabh Kumar, Arun Indian J Pharmacol Drug Watch Tuberculosis is a common infectious disease in developing countries. Isoniazid is established the first-line antitubercular drug and an essential component of all antitubercular regimens. Erythroderma caused by isoniazid is an uncommon but serious adverse drug reaction. We report here a case of a 63-year-old female patient who presented with generalized redness and scaling with itching after 8 weeks of antitubercular treatment (ATT). ATT was stopped immediately, and antihistaminics were started. The patient improved over a period of 2 weeks. On sequential rechallenge, she developed similar lesions all over the body with isoniazid, hence confirming the diagnosis of isoniazid-induced erythroderma. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4689027/ /pubmed/26729965 http://dx.doi.org/10.4103/0253-7613.169575 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Drug Watch
Garg, Yashika
Gore, Rajeshwari
Jain, Sourabh
Kumar, Arun
A rare case of isoniazid-induced erythroderma
title A rare case of isoniazid-induced erythroderma
title_full A rare case of isoniazid-induced erythroderma
title_fullStr A rare case of isoniazid-induced erythroderma
title_full_unstemmed A rare case of isoniazid-induced erythroderma
title_short A rare case of isoniazid-induced erythroderma
title_sort rare case of isoniazid-induced erythroderma
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689027/
https://www.ncbi.nlm.nih.gov/pubmed/26729965
http://dx.doi.org/10.4103/0253-7613.169575
work_keys_str_mv AT gargyashika ararecaseofisoniazidinducederythroderma
AT gorerajeshwari ararecaseofisoniazidinducederythroderma
AT jainsourabh ararecaseofisoniazidinducederythroderma
AT kumararun ararecaseofisoniazidinducederythroderma
AT gargyashika rarecaseofisoniazidinducederythroderma
AT gorerajeshwari rarecaseofisoniazidinducederythroderma
AT jainsourabh rarecaseofisoniazidinducederythroderma
AT kumararun rarecaseofisoniazidinducederythroderma

Ejemplares similares