The influence of paroxetine on the pharmacokinetics of atomoxetine and its main metabolite

BACKGROUND AND AIMS: To evaluate the effects of paroxetine on the pharmacokinetics of atomoxetine and its main metabolite, 4-hydroxyatomoxetine-O-glucuronide, after coadministration of atomoxetine and paroxetine in healthy volunteers. METHODS: 22 healthy volunteers, extensive metabolizers, took part...

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Detalles Bibliográficos
Autores principales: TODOR, IOANA, POPA, ADINA, NEAG, MARIA, MUNTEAN, DANA, BOCSAN, CORINA, BUZOIANU, ANCA, VLASE, LAURIAN, GHELDIU, ANA-MARIA, CHIRA, RUXANDRA, BRICIU, CORINA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iuliu Hatieganu University of Medicine and Pharmacy 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689245/
https://www.ncbi.nlm.nih.gov/pubmed/26733750
http://dx.doi.org/10.15386/cjmed-488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689245/
https://www.ncbi.nlm.nih.gov/pubmed/26733750
http://dx.doi.org/10.15386/cjmed-488

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