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Codon Usage in Signal Sequences Affects Protein Expression and Secretion Using Baculovirus/Insect Cell Expression System

By introducing synonymous mutations into the coding sequences of GP64sp and FibHsp signal peptides, the influences of mRNA secondary structure and codon usage of signal sequences on protein expression and secretion were investigated using baculovirus/insect cell expression system. The results showed...

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Detalles Bibliográficos
Autores principales:	Wang, Yalan, Mao, Yuanhui, Xu, Xiaodong, Tao, Shiheng, Chen, Hongying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689351/ https://www.ncbi.nlm.nih.gov/pubmed/26697848 http://dx.doi.org/10.1371/journal.pone.0145887

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