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Single-Tubed Wild-Type Blocking Quantitative PCR Detection Assay for the Sensitive Detection of Codon 12 and 13 KRAS Mutations

The high degree of intra-tumor heterogeneity has meant that it is important to develop sensitive and selective assays to detect low-abundance KRAS mutations in metastatic colorectal carcinoma (mCRC) patients. As a major potential source of tumor DNA in the aforementioned genotyping assays, it was ne...

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Detalles Bibliográficos
Autores principales:	Huang, Jun-Fu, Zeng, Dong-Zhu, Duan, Guang-Jie, Shi, Yan, Deng, Guo-Hong, Xia, Han, Xu, Han-Qing, Zhao, Na, Fu, Wei-Ling, Huang, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689371/ https://www.ncbi.nlm.nih.gov/pubmed/26701781 http://dx.doi.org/10.1371/journal.pone.0145698

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