Stable Human Hepatoma Cell Lines for Efficient Regulated Expression of Nucleoside/Nucleotide Analog Resistant and Vaccine Escape Hepatitis B Virus Variants and Woolly Monkey Hepatitis B Virus

Hepatitis B virus (HBV) causes acute and chronic hepatitis B (CHB). Due to its error-prone replication via reverse transcription, HBV can rapidly evolve variants that escape vaccination and/or become resistant to CHB treatment with nucleoside/nucleotide analogs (NAs). This is particularly problemati...

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Detalles Bibliográficos
Autores principales: Cheng, Xin, Guan, Weiwei, Sun, Shuo, Li, Baosheng, Li, Haijun, Kang, Fubiao, Kang, Jiwen, Yang, Dongliang, Nassal, Michael, Sun, Dianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689378/
https://www.ncbi.nlm.nih.gov/pubmed/26699621
http://dx.doi.org/10.1371/journal.pone.0145746

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