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Origin-Dependent Inverted-Repeat Amplification: Tests of a Model for Inverted DNA Amplification

DNA replication errors are a major driver of evolution—from single nucleotide polymorphisms to large-scale copy number variations (CNVs). Here we test a specific replication-based model to explain the generation of interstitial, inverted triplications. While no genetic information is lost, the novel...

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Detalles Bibliográficos
Autores principales:	Brewer, Bonita J., Payen, Celia, Di Rienzi, Sara C., Higgins, Megan M., Ong, Giang, Dunham, Maitreya J., Raghuraman, M. K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689423/ https://www.ncbi.nlm.nih.gov/pubmed/26700858 http://dx.doi.org/10.1371/journal.pgen.1005699

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