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Crystal Structure of OXA-58 with the Substrate-Binding Cleft in a Closed State: Insights into the Mobility and Stability of the OXA-58 Structure

OXA-58 is a class D β-lactamase from the multi-drug resistant Acinetobacter baumannii. We determined the crystal structure of OXA-58 in a novel crystal, and revealed the structure of the substrate-binding cleft in a closed state, distinct from a previously reported OXA-58 crystal structure with the...

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Detalles Bibliográficos
Autores principales:	Saino, Hiromichi, Sugiyabu, Tomohiro, Ueno, Go, Yamamoto, Masaki, Ishii, Yoshikazu, Miyano, Masashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689445/ https://www.ncbi.nlm.nih.gov/pubmed/26701320 http://dx.doi.org/10.1371/journal.pone.0145869

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