Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis

BACKGROUND: Immucillins ImmA (IA), ImmH (IH) and SerMe-ImmH (SMIH) are synthetic deazapurine nucleoside analogues that inhibit Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis multiplication in vitro without macrophage toxicity. Immucillins are compared to the Glucantime standard dru...

Descripción completa

Detalles Bibliográficos
Autores principales: Freitas, Elisangela Oliveira, Nico, Dirlei, Alves-Silva, Marcus Vinícius, Morrot, Alexandre, Clinch, Keith, Evans, Gary B., Tyler, Peter C., Schramm, Vern L., Palatnik-de-Sousa, Clarisa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689457/
https://www.ncbi.nlm.nih.gov/pubmed/26701750
http://dx.doi.org/10.1371/journal.pntd.0004297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689457/
https://www.ncbi.nlm.nih.gov/pubmed/26701750
http://dx.doi.org/10.1371/journal.pntd.0004297

Ejemplares similares