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Immucillins ImmA and ImmH Are Effective and Non-toxic in the Treatment of Experimental Visceral Leishmaniasis
BACKGROUND: Immucillins ImmA (IA), ImmH (IH) and SerMe-ImmH (SMIH) are synthetic deazapurine nucleoside analogues that inhibit Leishmania (L.) infantum chagasi and Leishmania (L.) amazonensis multiplication in vitro without macrophage toxicity. Immucillins are compared to the Glucantime standard dru...
Autores principales: | Freitas, Elisangela Oliveira, Nico, Dirlei, Alves-Silva, Marcus Vinícius, Morrot, Alexandre, Clinch, Keith, Evans, Gary B., Tyler, Peter C., Schramm, Vern L., Palatnik-de-Sousa, Clarisa B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689457/ https://www.ncbi.nlm.nih.gov/pubmed/26701750 http://dx.doi.org/10.1371/journal.pntd.0004297 |
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