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Elastohydrodynamics and Kinetics of Protein Patterning in the Immunological Synapse

We propose a minimal mathematical model for the physical basis of membrane protein patterning in the immunological synapse (IS), which encompass membrane mechanics, protein binding kinetics and motion, and fluid flow in the synaptic cleft. Our theory leads to simple predictions for the spatial and t...

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Detalles Bibliográficos
Autores principales: Carlson, Andreas, Mahadevan, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689476/
https://www.ncbi.nlm.nih.gov/pubmed/26699430
http://dx.doi.org/10.1371/journal.pcbi.1004481