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Elastohydrodynamics and Kinetics of Protein Patterning in the Immunological Synapse
We propose a minimal mathematical model for the physical basis of membrane protein patterning in the immunological synapse (IS), which encompass membrane mechanics, protein binding kinetics and motion, and fluid flow in the synaptic cleft. Our theory leads to simple predictions for the spatial and t...
Autores principales: | Carlson, Andreas, Mahadevan, L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689476/ https://www.ncbi.nlm.nih.gov/pubmed/26699430 http://dx.doi.org/10.1371/journal.pcbi.1004481 |
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