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The Molecular Engineering of an Anti-Idiotypic Antibody for Pharmacokinetic Analysis of a Fully Human Anti-Infective

Anti-idiotype monoclonal antibodies represent a class of reagents that are potentially optimal for analyzing the pharmacokinetics of fully human, anti-infective antibodies that have been developed as therapeutic candidates. This is particularly important where direct pathogen binding assays are comp...

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Detalles Bibliográficos
Autores principales: Lim, She Yah, Chan, Conrad E. Z., Lisowska, Malgorzata M., Hanson, Brendon J., MacAry, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689483/
https://www.ncbi.nlm.nih.gov/pubmed/26700297
http://dx.doi.org/10.1371/journal.pone.0145381