Biliary tract cancers: SEOM clinical guidelines

Biliary tract cancer (BTC) is an uncommon and highly fatal malignancy. It is composed of three main different entities; Gall bladder carcinoma (GBC), intrahepatic cholangiocarcinoma (iCC) and extrahepatic cholangiocarcinoma (eCC) sharing different genetic, risk factors and clinical presentation. Mul...

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Autores principales: Benavides, M., Antón, A., Gallego, J., Gómez, M. A., Jiménez-Gordo, A., La Casta, A., Laquente, B., Macarulla, T., Rodríguez-Mowbray, J. R., Maurel, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2015
Materias:
Clinical Guides in Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689747/
https://www.ncbi.nlm.nih.gov/pubmed/26607930
http://dx.doi.org/10.1007/s12094-015-1436-2
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author Benavides, M.
Antón, A.
Gallego, J.
Gómez, M. A.
Jiménez-Gordo, A.
La Casta, A.
Laquente, B.
Macarulla, T.
Rodríguez-Mowbray, J. R.
Maurel, J.
author_facet Benavides, M.
Antón, A.
Gallego, J.
Gómez, M. A.
Jiménez-Gordo, A.
La Casta, A.
Laquente, B.
Macarulla, T.
Rodríguez-Mowbray, J. R.
Maurel, J.
author_sort Benavides, M.
collection PubMed
description Biliary tract cancer (BTC) is an uncommon and highly fatal malignancy. It is composed of three main different entities; Gall bladder carcinoma (GBC), intrahepatic cholangiocarcinoma (iCC) and extrahepatic cholangiocarcinoma (eCC) sharing different genetic, risk factors and clinical presentation. Multidetector-row computed tomography (MDCT) and magnetic resonance cholangio-pancreatography (MRCP) are the more important diagnostic techniques. Surgery is the only potentially curative therapy but disease recurrence is frequent. Treatment with chemotherapy, radiotherapy or both has not demonstrated survival benefit in the adjuvant setting. Cisplatin plus gemcitabine constitutes the gold standard in metastatic disease. New ongoing studies mainly in the adjuvant and neoadjuvant setting along with molecular research will hopefully help to improve survival and quality of life of this disease.
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spelling pubmed-46897472015-12-31 Biliary tract cancers: SEOM clinical guidelines Benavides, M. Antón, A. Gallego, J. Gómez, M. A. Jiménez-Gordo, A. La Casta, A. Laquente, B. Macarulla, T. Rodríguez-Mowbray, J. R. Maurel, J. Clin Transl Oncol Clinical Guides in Oncology Biliary tract cancer (BTC) is an uncommon and highly fatal malignancy. It is composed of three main different entities; Gall bladder carcinoma (GBC), intrahepatic cholangiocarcinoma (iCC) and extrahepatic cholangiocarcinoma (eCC) sharing different genetic, risk factors and clinical presentation. Multidetector-row computed tomography (MDCT) and magnetic resonance cholangio-pancreatography (MRCP) are the more important diagnostic techniques. Surgery is the only potentially curative therapy but disease recurrence is frequent. Treatment with chemotherapy, radiotherapy or both has not demonstrated survival benefit in the adjuvant setting. Cisplatin plus gemcitabine constitutes the gold standard in metastatic disease. New ongoing studies mainly in the adjuvant and neoadjuvant setting along with molecular research will hopefully help to improve survival and quality of life of this disease. Springer Milan 2015-11-25 2015 /pmc/articles/PMC4689747/ /pubmed/26607930 http://dx.doi.org/10.1007/s12094-015-1436-2 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Clinical Guides in Oncology
Benavides, M.
Antón, A.
Gallego, J.
Gómez, M. A.
Jiménez-Gordo, A.
La Casta, A.
Laquente, B.
Macarulla, T.
Rodríguez-Mowbray, J. R.
Maurel, J.
Biliary tract cancers: SEOM clinical guidelines
title Biliary tract cancers: SEOM clinical guidelines
title_full Biliary tract cancers: SEOM clinical guidelines
title_fullStr Biliary tract cancers: SEOM clinical guidelines
title_full_unstemmed Biliary tract cancers: SEOM clinical guidelines
title_short Biliary tract cancers: SEOM clinical guidelines
title_sort biliary tract cancers: seom clinical guidelines
topic Clinical Guides in Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689747/
https://www.ncbi.nlm.nih.gov/pubmed/26607930
http://dx.doi.org/10.1007/s12094-015-1436-2
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