Cargando…
Cognitive Impairment after Severe Traumatic Brain Injury, Clinical Course and Impact on Outcome: A Swedish-Icelandic Study
Objective. To assess the clinical course of cognitive and emotional impairments in patients with severe TBI (sTBI) from 3 weeks to 1 year after trauma and to study associations with outcomes at 1 year. Methods. Prospective, multicenter, observational study of sTBI in Sweden and Iceland. Patients age...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689900/ https://www.ncbi.nlm.nih.gov/pubmed/26783381 http://dx.doi.org/10.1155/2015/680308 |
_version_ | 1782406915346661376 |
---|---|
author | Stenberg, Maud Godbolt, Alison K. Nygren De Boussard, Catharina Levi, Richard Stålnacke, Britt-Marie |
author_facet | Stenberg, Maud Godbolt, Alison K. Nygren De Boussard, Catharina Levi, Richard Stålnacke, Britt-Marie |
author_sort | Stenberg, Maud |
collection | PubMed |
description | Objective. To assess the clinical course of cognitive and emotional impairments in patients with severe TBI (sTBI) from 3 weeks to 1 year after trauma and to study associations with outcomes at 1 year. Methods. Prospective, multicenter, observational study of sTBI in Sweden and Iceland. Patients aged 18–65 years with acute Glasgow Coma Scale 3–8 were assessed with the Barrow Neurological Institute Screen for Higher Cerebral Functions (BNIS) and the Hospital Anxiety and Depression Scale (HADS). Outcome measures were Glasgow Outcome Scale Extended (GOSE) and Rancho Los Amigos Cognitive Scale-Revised (RLAS-R). Results. Cognition was assessed with the BNIS assessed for 42 patients out of 100 at 3 weeks, 75 patients at 3 months, and 78 patients at 1 year. Cognition improved over time, especially from 3 weeks to 3 months. The BNIS subscales “orientation” and “visuospatial and visual problem solving” were associated with the GOSE and RLAS-R at 1 year. Conclusion. Cognition seemed to improve over time after sTBI and appeared to be rather stable from 3 months to 1 year. Since cognitive function was associated with outcomes, these results indicate that early screening of cognitive function could be of importance for rehabilitation planning in a clinical setting. |
format | Online Article Text |
id | pubmed-4689900 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-46899002016-01-18 Cognitive Impairment after Severe Traumatic Brain Injury, Clinical Course and Impact on Outcome: A Swedish-Icelandic Study Stenberg, Maud Godbolt, Alison K. Nygren De Boussard, Catharina Levi, Richard Stålnacke, Britt-Marie Behav Neurol Research Article Objective. To assess the clinical course of cognitive and emotional impairments in patients with severe TBI (sTBI) from 3 weeks to 1 year after trauma and to study associations with outcomes at 1 year. Methods. Prospective, multicenter, observational study of sTBI in Sweden and Iceland. Patients aged 18–65 years with acute Glasgow Coma Scale 3–8 were assessed with the Barrow Neurological Institute Screen for Higher Cerebral Functions (BNIS) and the Hospital Anxiety and Depression Scale (HADS). Outcome measures were Glasgow Outcome Scale Extended (GOSE) and Rancho Los Amigos Cognitive Scale-Revised (RLAS-R). Results. Cognition was assessed with the BNIS assessed for 42 patients out of 100 at 3 weeks, 75 patients at 3 months, and 78 patients at 1 year. Cognition improved over time, especially from 3 weeks to 3 months. The BNIS subscales “orientation” and “visuospatial and visual problem solving” were associated with the GOSE and RLAS-R at 1 year. Conclusion. Cognition seemed to improve over time after sTBI and appeared to be rather stable from 3 months to 1 year. Since cognitive function was associated with outcomes, these results indicate that early screening of cognitive function could be of importance for rehabilitation planning in a clinical setting. Hindawi Publishing Corporation 2015 2015-12-09 /pmc/articles/PMC4689900/ /pubmed/26783381 http://dx.doi.org/10.1155/2015/680308 Text en Copyright © 2015 Maud Stenberg et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Stenberg, Maud Godbolt, Alison K. Nygren De Boussard, Catharina Levi, Richard Stålnacke, Britt-Marie Cognitive Impairment after Severe Traumatic Brain Injury, Clinical Course and Impact on Outcome: A Swedish-Icelandic Study |
title | Cognitive Impairment after Severe Traumatic Brain Injury, Clinical Course and Impact on Outcome: A Swedish-Icelandic Study |
title_full | Cognitive Impairment after Severe Traumatic Brain Injury, Clinical Course and Impact on Outcome: A Swedish-Icelandic Study |
title_fullStr | Cognitive Impairment after Severe Traumatic Brain Injury, Clinical Course and Impact on Outcome: A Swedish-Icelandic Study |
title_full_unstemmed | Cognitive Impairment after Severe Traumatic Brain Injury, Clinical Course and Impact on Outcome: A Swedish-Icelandic Study |
title_short | Cognitive Impairment after Severe Traumatic Brain Injury, Clinical Course and Impact on Outcome: A Swedish-Icelandic Study |
title_sort | cognitive impairment after severe traumatic brain injury, clinical course and impact on outcome: a swedish-icelandic study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689900/ https://www.ncbi.nlm.nih.gov/pubmed/26783381 http://dx.doi.org/10.1155/2015/680308 |
work_keys_str_mv | AT stenbergmaud cognitiveimpairmentafterseveretraumaticbraininjuryclinicalcourseandimpactonoutcomeaswedishicelandicstudy AT godboltalisonk cognitiveimpairmentafterseveretraumaticbraininjuryclinicalcourseandimpactonoutcomeaswedishicelandicstudy AT nygrendeboussardcatharina cognitiveimpairmentafterseveretraumaticbraininjuryclinicalcourseandimpactonoutcomeaswedishicelandicstudy AT levirichard cognitiveimpairmentafterseveretraumaticbraininjuryclinicalcourseandimpactonoutcomeaswedishicelandicstudy AT stalnackebrittmarie cognitiveimpairmentafterseveretraumaticbraininjuryclinicalcourseandimpactonoutcomeaswedishicelandicstudy |