Development and Validation of Simple RP-HPLC Method for Intracellular Determination of Fluconazole Concentration and Its Application to the Study of Candida albicans Azole Resistance

Candida albicans (strains NCTC-885-653 and ATCC-10231) long-term cultivated in the presence of antifungal agent fluconazole (FLC) and classical microbiological methods for determination of minimal inhibitory concentration (MIC) were used in this study. A simple and sensitive method based on reverse-...

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Detalles Bibliográficos
Autores principales: Davtyan, Tigran K., Melikyan, Levon A., Nikoyan, Nune A., Aleksanyan, Hripsime P., Grigoryan, Nairi G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689911/
https://www.ncbi.nlm.nih.gov/pubmed/26783393
http://dx.doi.org/10.1155/2015/576250

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