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Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients

Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal hematopoietic disorders. MDS is frequently associated with deletions on chromosome 5q as well as aberrant DNA methylation patterns including hypermethylation of key tumor suppressors. We have previously shown that hypermethylation and...

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Detalles Bibliográficos
Autores principales: Søgaard Helbo, Alexandra, Treppendahl, Marianne, Aslan, Derya, Dimopoulos, Konstantinos, Nandrup-Bus, Cecilie, Holm, Mette Skov, Andersen, Mette Klarskov, Liang, Gangning, Kristensen, Lasse Sommer, Grønbæk, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690025/
https://www.ncbi.nlm.nih.gov/pubmed/26473932
http://dx.doi.org/10.3390/genes6040977