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Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients
Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal hematopoietic disorders. MDS is frequently associated with deletions on chromosome 5q as well as aberrant DNA methylation patterns including hypermethylation of key tumor suppressors. We have previously shown that hypermethylation and...
Autores principales: | Søgaard Helbo, Alexandra, Treppendahl, Marianne, Aslan, Derya, Dimopoulos, Konstantinos, Nandrup-Bus, Cecilie, Holm, Mette Skov, Andersen, Mette Klarskov, Liang, Gangning, Kristensen, Lasse Sommer, Grønbæk, Kirsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690025/ https://www.ncbi.nlm.nih.gov/pubmed/26473932 http://dx.doi.org/10.3390/genes6040977 |
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