Cargando…

Use of Monoclonal Antibodies in the Sensitive Detection and Neutralization of Botulinum Neurotoxin Serotype B

Botulinum neurotoxins (BoNT) are some of nature’s most potent toxins. Due to potential food contamination, and bioterrorism concerns, the development of detection reagents, therapeutics and countermeasures are of urgent interest. Recently, we have developed a sensitive electrochemiluminescent (ECL)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Luisa W., Henderson, Thomas D., Lam, Tina I., Stanker, Larry H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690113/ https://www.ncbi.nlm.nih.gov/pubmed/26633496 http://dx.doi.org/10.3390/toxins7124863

Ejemplares similares

A Monoclonal Antibody Based Capture ELISA for Botulinum Neurotoxin Serotype B: Toxin Detection in Food
por: Stanker, Larry H., et al.
Publicado: (2013)

Probiotic Microorganisms Inhibit Epithelial Cell Internalization of Botulinum Neurotoxin Serotype A
por: Lam, Tina I., et al.
Publicado: (2016)

Translocation of botulinum neurotoxin serotype A and associated proteins across the intestinal epithelia
por: Lam, Tina I, et al.
Publicado: (2015)

Development and Characterization of Monoclonal Antibodies to Botulinum Neurotoxin Type E
por: Bever, Candace S., et al.
Publicado: (2019)

Fully Human Monoclonal Antibodies Effectively Neutralizing Botulinum Neurotoxin Serotype B
por: Matsumura, Takuhiro, et al.
Publicado: (2020)

Detection of Botulinum Neurotoxin Serotype B at Sub Mouse LD(50) Levels by a Sandwich Immunoassay and Its Application to Toxin Detection in Milk
por: Scotcher, Miles C., et al.
Publicado: (2010)

Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B
por: Fan, Yongfeng, et al.
Publicado: (2015)

A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes
por: Garcia-Rodriguez, Consuelo, et al.
Publicado: (2018)

A three monoclonal antibody combination potently neutralizes multiple botulinum neurotoxin serotype F subtypes
por: Fan, Yongfeng, et al.
Publicado: (2017)

A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D
por: Garcia-Rodriguez, Consuelo, et al.
Publicado: (2021)

A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A
por: Lou, Jianlong, et al.
Publicado: (2018)

A human bispecific antibody neutralizes botulinum neurotoxin serotype A
por: Lu, Jiansheng, et al.
Publicado: (2023)

Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function
por: Tremblay, Jacqueline M., et al.
Publicado: (2020)

Rapid Microfluidic Assay for the Detection of Botulinum Neurotoxin in Animal Sera
por: Babrak, Lmar, et al.
Publicado: (2016)

A Simple, Rapid and Sensitive FRET Assay for Botulinum Neurotoxin Serotype B Detection
por: Guo, Jiubiao, et al.
Publicado: (2014)

Functional detection of botulinum neurotoxin serotypes A to F by monoclonal neoepitope-specific antibodies and suspension array technology
por: von Berg, Laura, et al.
Publicado: (2019)

Monoclonal Antibodies Targeting the Alpha-Exosite of Botulinum Neurotoxin Serotype/A Inhibit Catalytic Activity
por: Fan, Yongfeng, et al.
Publicado: (2015)

Mouse in Vivo Neutralization of Escherichia coli Shiga Toxin 2 with Monoclonal Antibodies
por: Cheng, Luisa W., et al.
Publicado: (2013)

Neutralization of Botulinum Neurotoxin by a Human Monoclonal Antibody Specific for the Catalytic Light Chain
por: Adekar, Sharad P., et al.
Publicado: (2008)

Epitope Characterization and Variable Region Sequence of F1-40, a High-Affinity Monoclonal Antibody to Botulinum Neurotoxin Type A (Hall Strain)
por: Scotcher, Miles C., et al.
Publicado: (2009)

Botulinum Neurotoxin Serotypes Detected by Electrochemical Impedance Spectroscopy
por: Savage, Alison C., et al.
Publicado: (2015)

Emerging Opportunities for Serotypes of Botulinum Neurotoxins
por: Peng Chen, Zhongxing, et al.
Publicado: (2012)

Correction: Epitope Characterization and Variable Region Sequence of F1-40, a High-Affinity Monoclonal Antibody to Botulinum Neurotoxin Type A (Hall Strain)
por: Scotcher, Miles C., et al.
Publicado: (2009)

Correction: Epitope Characterization and Variable Region Sequence of F1-40, a High-Affinity Monoclonal Antibody to Botulinum Neurotoxin Type A (Hall Strain)
por: Scotcher, Miles C., et al.
Publicado: (2009)

Correction: Epitope Characterization and Variable Region Sequence of F1-40, a High-Affinity Monoclonal Antibody to Botulinum Neurotoxin Type A (Hall Strain)
por: Scotcher, Miles C., et al.
Publicado: (2009)

Zebrafish Sensitivity to Botulinum Neurotoxins
por: Chatla, Kamalakar, et al.
Publicado: (2016)

A Rapid, Sensitive, and Portable Biosensor Assay for the Detection of Botulinum Neurotoxin Serotype A in Complex Food Matrices
por: Tam, Christina C., et al.
Publicado: (2018)

Immunological Characterization and Neutralizing Ability of Monoclonal Antibodies Directed Against Botulinum Neurotoxin Type H
por: Fan, Yongfeng, et al.
Publicado: (2016)

Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B
por: Miethe, Sebastian, et al.
Publicado: (2016)

Botulinum Neurotoxin Detection Methods for Public Health Response and Surveillance
por: Thirunavukkarasu, Nagarajan, et al.
Publicado: (2018)

Characterization of Botulinum Neurotoxin Type A Neutralizing Monoclonal Antibodies and Influence of Their Half-Lives on Therapeutic Activity
por: Mazuet, Christelle, et al.
Publicado: (2010)

Neutralization of Botulinum Neurotoxin Type E by a Humanized Antibody
por: Derman, Yağmur, et al.
Publicado: (2016)

Development of immunodetection system for botulinum neurotoxin serotype E
por: Sarita, R., et al.
Publicado: (2018)

Single-Domain Antibody Multimers for Detection of Botulinum Neurotoxin Serotypes C, D, and Their Mosaics in Endopep-MS
por: Harmsen, Michiel M., et al.
Publicado: (2023)

Characterization of Serotype CD Mosaic Botulinum Neurotoxin in Comparison with Serotype C and A
por: Miyashita, Shin-Ichiro, et al.
Publicado: (2023)

Llama Single Domain Antibodies Specific for the 7 Botulinum Neurotoxin Serotypes as Heptaplex Immunoreagents
por: Conway, Jerry O., et al.
Publicado: (2010)

Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin
por: Weisemann, Jasmin, et al.
Publicado: (2016)

Sheep Monoclonal Antibodies Prevent Systemic Effects of Botulinum Neurotoxin A1
por: Mukherjee, Jean, et al.
Publicado: (2012)

Mechanism of Ganglioside Receptor Recognition by Botulinum Neurotoxin Serotype E
por: Masuyer, Geoffrey, et al.
Publicado: (2021)

Recombinant botulinum neurotoxin serotype A1 in vivo characterization
por: Périer, Cindy, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jomgff11l5u0opegj8tkciatp7