A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions

BACKGROUND: Genetic interactions, or non-additive effects between genes, play a crucial role in many cellular processes and disease. Which mechanisms underlie these genetic interactions has hardly been characterized. Understanding the molecular basis of genetic interactions is crucial in deciphering...

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Detalles Bibliográficos
Autores principales: Sameith, Katrin, Amini, Saman, Groot Koerkamp, Marian J. A., van Leenen, Dik, Brok, Mariel, Brabers, Nathalie, Lijnzaad, Philip, van Hooff, Sander R., Benschop, Joris J., Lenstra, Tineke L., Apweiler, Eva, van Wageningen, Sake, Snel, Berend, Holstege, Frank C. P., Kemmeren, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690272/
https://www.ncbi.nlm.nih.gov/pubmed/26700642
http://dx.doi.org/10.1186/s12915-015-0222-5

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