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A forest-based feature screening approach for large-scale genome data with complex structures

BACKGROUND: Genome-wide association studies (GWAS) interrogate large-scale whole genome to characterize the complex genetic architecture for biomedical traits. When the number of SNPs dramatically increases to half million but the sample size is still limited to thousands, the traditional p-value ba...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Fu, Guifang, Corcoran, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690313/
https://www.ncbi.nlm.nih.gov/pubmed/26698561
http://dx.doi.org/10.1186/s12863-015-0294-9