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A forest-based feature screening approach for large-scale genome data with complex structures
BACKGROUND: Genome-wide association studies (GWAS) interrogate large-scale whole genome to characterize the complex genetic architecture for biomedical traits. When the number of SNPs dramatically increases to half million but the sample size is still limited to thousands, the traditional p-value ba...
Autores principales: | Wang, Gang, Fu, Guifang, Corcoran, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690313/ https://www.ncbi.nlm.nih.gov/pubmed/26698561 http://dx.doi.org/10.1186/s12863-015-0294-9 |
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