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Wnt signaling and the developmental fate of lung cells
Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias.
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2004
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC469033/ https://www.ncbi.nlm.nih.gov/pubmed/15225354 http://dx.doi.org/10.1186/jbiol9 |
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author | Clayton, Julie |
author_facet | Clayton, Julie |
author_sort | Clayton, Julie |
collection | PubMed |
description | Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias. |
format | Text |
id | pubmed-469033 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2004 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-4690332004-07-16 Wnt signaling and the developmental fate of lung cells Clayton, Julie J Biol Research News Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias. BioMed Central 2004 2004-06-28 /pmc/articles/PMC469033/ /pubmed/15225354 http://dx.doi.org/10.1186/jbiol9 Text en Copyright © 2004 BioMed Central Ltd |
spellingShingle | Research News Clayton, Julie Wnt signaling and the developmental fate of lung cells |
title | Wnt signaling and the developmental fate of lung cells |
title_full | Wnt signaling and the developmental fate of lung cells |
title_fullStr | Wnt signaling and the developmental fate of lung cells |
title_full_unstemmed | Wnt signaling and the developmental fate of lung cells |
title_short | Wnt signaling and the developmental fate of lung cells |
title_sort | wnt signaling and the developmental fate of lung cells |
topic | Research News |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC469033/ https://www.ncbi.nlm.nih.gov/pubmed/15225354 http://dx.doi.org/10.1186/jbiol9 |
work_keys_str_mv | AT claytonjulie wntsignalingandthedevelopmentalfateoflungcells |