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Wnt signaling and the developmental fate of lung cells

Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias.

Detalles Bibliográficos
Autor principal: Clayton, Julie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC469033/
https://www.ncbi.nlm.nih.gov/pubmed/15225354
http://dx.doi.org/10.1186/jbiol9
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author Clayton, Julie
author_facet Clayton, Julie
author_sort Clayton, Julie
collection PubMed
description Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias.
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spelling pubmed-4690332004-07-16 Wnt signaling and the developmental fate of lung cells Clayton, Julie J Biol Research News Constitutive activation of the Wnt signaling pathway during lung development in mouse embryos causes some cells to develop a gut-like phenotype. These findings are reminiscent of classical embryological experiments and may have therapeutic implications for pre-cancerous metaplasias. BioMed Central 2004 2004-06-28 /pmc/articles/PMC469033/ /pubmed/15225354 http://dx.doi.org/10.1186/jbiol9 Text en Copyright © 2004 BioMed Central Ltd
spellingShingle Research News
Clayton, Julie
Wnt signaling and the developmental fate of lung cells
title Wnt signaling and the developmental fate of lung cells
title_full Wnt signaling and the developmental fate of lung cells
title_fullStr Wnt signaling and the developmental fate of lung cells
title_full_unstemmed Wnt signaling and the developmental fate of lung cells
title_short Wnt signaling and the developmental fate of lung cells
title_sort wnt signaling and the developmental fate of lung cells
topic Research News
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC469033/
https://www.ncbi.nlm.nih.gov/pubmed/15225354
http://dx.doi.org/10.1186/jbiol9
work_keys_str_mv AT claytonjulie wntsignalingandthedevelopmentalfateoflungcells