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A map of sphingosine 1-phosphate distribution in the spleen

Despite the importance of signaling lipids, many questions remain about their function because we have few tools to chart lipid gradients in vivo. Here we describe a sphingosine 1-phosphate (S1P) reporter mouse, and use this mouse to define S1P distribution in the spleen. Surprisingly, the presence...

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Detalles Bibliográficos
Autores principales: Ramos-Perez, Willy D., Fang, Victoria, Escalante-Alcalde, Diana, Cammer, Michael, Schwab, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690472/
https://www.ncbi.nlm.nih.gov/pubmed/26502404
http://dx.doi.org/10.1038/ni.3296