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Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer

A gene drug delivery system for glioma therapy based on transferrin (Tf)-modified polyamidoamine dendrimer (PAMAM) was prepared. Gene drug, tumor necrosis factor-related apoptosis-inducing ligand (hTRAIL)-encoding plasmid open reading frame (pORF-hTRAIL, Trail), was condensed by Tf-modified PAMAM to...

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Detalles Bibliográficos
Autores principales: Gao, Song, Li, Jianfeng, Jiang, Chen, Hong, Bo, Hao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690643/
https://www.ncbi.nlm.nih.gov/pubmed/26719669
http://dx.doi.org/10.2147/DDDT.S95843