HIV-1-Induced Small T Cell Syncytia Can Transfer Virus Particles to Target Cells through Transient Contacts

HIV-1 Env mediates fusion of viral and target cell membranes, but it can also mediate fusion of infected (producer) and target cells, thus triggering the formation of multinucleated cells, so-called syncytia. Large, round, immobile syncytia are readily observable in cultures of HIV-1-infected T cell...

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Detalles Bibliográficos
Autores principales: Symeonides, Menelaos, Murooka, Thomas T., Bellfy, Lauren N., Roy, Nathan H., Mempel, Thorsten R., Thali, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690882/
https://www.ncbi.nlm.nih.gov/pubmed/26703714
http://dx.doi.org/10.3390/v7122959

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