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Glucose-6-Phosphate Dehydrogenase Enhances Antiviral Response through Downregulation of NADPH Sensor HSCARG and Upregulation of NF-κB Signaling
Glucose-6-phosphate dehydrogenase (G6PD)-deficient cells are highly susceptible to viral infection. This study examined the mechanism underlying this phenomenon by measuring the expression of antiviral genes—tumor necrosis factor alpha (TNF-α) and GTPase myxovirus resistance 1 (MX1)—in G6PD-knockdow...
Autores principales: | Wu, Yi-Hsuan, Chiu, Daniel Tsun-Yee, Lin, Hsin-Ru, Tang, Hsiang-Yu, Cheng, Mei-Ling, Ho, Hung-Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4690889/ https://www.ncbi.nlm.nih.gov/pubmed/26694452 http://dx.doi.org/10.3390/v7122966 |
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